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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

致以最良好的祝福,原你新年快乐幸福。
fF&h#Y~]lvc

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Comparing regions within specific categories of costs, the EIU notes that Asian cities are the most expensive for grocery shopping, with Seoul in South Korea the priciest for food. European cities are the most expensive in terms of recreation and entertainment.
fMyMcOap+fQw~Mwi)uNa

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Common industries for college startups include catering, agriculture, IT, transportation, education and culture. 13.8% of the entrepreneurs were interested in hospitality and catering, while 13.7% chose agriculture, the report said.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

In contrast, the average unit price of emerging market exports has been falling in year-on-year terms pretty much since mid-2012, hitting a year-on-year decline of 16.4 per cent in February 2016.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Isolated in northern China, this virus was similar to the virus that spread before 1957. For this reason, individuals born before 1957 were generally protected, however children and young adults born after that year were not because they had no prior immunity. By January 1978, the virus had spread around the world, including the United States. Because illness occurred primarily in children, this event was not considered a true pandemic. Vaccine containing this virus was not produced in time for the 1977-78 season, but the virus was included in the 1978-79 vaccine.
The U.S. will perform well even if the rest of the world doesn't
Variety Talk Series: “Last Week Tonight With John Oliver” (HBO)
There is still tremendous untapped potential in China-Russia economic and trade ties and the two economies are highly complementary. The goals set for the two-way trade can be achieved.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

日本总体排名第五,是亚洲表现最优异的国家。“原动力”排名第五,“前瞻性”排名第一。
A panel of eight WardsAuto editors evaluated 44 engines among all vehicle types during October and November in the course of their daily commutes and weekend activities in and around the Detroit metro area. Engines were rated according to a wide range of characteristics including horsepower and torque, fuel economy, noise, vibration and harshness characteristics, technology and how they fared against competing powerplants.
“只要总体市场仍然相对积极,只要交易继续执行良好,我们继续预期今年余下时间会保持健康的交易量,”高盛(Goldman Sachs)美洲股票资本市场主管戴维?路德维格(David Ludwig)表示。
1、Procrastination

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

但这种理念不会让英国退欧或者让特朗普当选总统。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 中国塑钢型材市场的新趋势
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The actress who kick-started the exposure of Hollywood moguls who allegedly exploited positions of power to abuse women has branded #MeToo campaigners against sex attackers 'losers'.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

n. 品质,特质,才能
不过,漫长的收缩期也符合正在放缓的中国经济的总体趋势。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

年龄:43岁
巴蒂说道:“纵观亚洲高校前三百名榜单,我们可以看到,现如今,动态、多样化且颇具竞争力的高等教育园区正在亚洲地区逐渐形成,中国则是这个发展过程中极其重要的一部分。”

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

昨日发布的央行数据显示,中国外汇储备上月出现有记录以来第三大单月降幅。这重燃了人们对于中国遭遇资本外流的担忧,此前中国外汇储备似乎企稳。
祝老师新年充满平安和爱。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 部分上市公司折价甩卖房产
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

单词ridiculous 联想记忆:
老虎要入眠,鸟儿要降落;
曼诺拉·达吉斯
"这个家伙对当前情况作了利弊权衡:他有很大机会从故障电梯逃生,但是如果家庭作业没完成,他会很倒霉。"一名名为Zealshifang的用户调侃道。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Among 36,000 who have reached celebrity status on the Internet, 74 percent are women and 87.8 percent are between 17 to 33 years old, while 89 percent have a college education. Followers are also getting younger and better educated, with 77.8 percent in the 17-to-33 age group and 75 percent with a higher education.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Two weeks later, Mr. Bernheimer was among the dozens of long-established old master dealers attending the London evening sales. In the past, they would buy at these auctions to stock up for the Maastricht European Fine Art Fair in March in the Netherlands. But with sellers encouraging Sotheby’s and Christie’s to compete for their business with ever-higher valuations, and auctions now marketed to a shallow pool of wealthy buyers, there was conspicuously little trade bidding.
He slipped a note through the door with the message "People stuck inside, please ask the property management for help," and hoped someone would pick it up and act on it.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 威宁西南水泥余热发电运行并网
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

那些服装能引起共鸣,是因为身穿那些服装的剧中人物精致复杂,而不只是因为琼的织锦紧身连衣裙真的魅力四射,或者梅根的迷幻雪纺连衣裙让璞琪看起来很酷。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 隐藏在橱柜中的铰链的“秘密”
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

凯投宏观(Capital Economics)首席亚洲经济学家马克?威廉姆斯(Mark Williams)补充道:“我们预计,2017年新兴市场出口的表现将继续改善,出口值会同比温和增长。”

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

A New Year greeting to cheer you, my good friend.希望新年祝福给你带来欢乐,我的好朋友。
Headquarter shifts: With Toyota leaving for Texas and Mercedes headed toward North Carolina or Georgia from New Jersey, look for Subaru to chart its own path when it builds its new headquarters. One option: Moving closer to its customers by relocating in Vermont.
Experts say that 2016 was a remarkable year for the Chinese film industry as it realized growth while facing multiple challenges including the rapid development of the internet, the increasingly sophisticated tastes of Chinese audiences, and the economic downturn in the country.
The U.S. will perform well even if the rest of the world doesn't

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Earlier on Tuesday Mr Rutte had issued a call for calm in the dispute with Turkey.
During last year's LFW, there were 250 anti-fur protesters, The Guardian reported, and a show in February saw an activist storm the stage at a Mary Katrantzou show.
洛德《情景剧》
在1月10日发表的一条推文中,奥巴马写道:“感谢你们为我做的一切。我最后一个请求和第一个一样。我请求你们不要相信我的而要相信你们自己的创造改变的能力。”
具体来说,广电总局表示,2016年中国票房总额达到457亿元人民币(约66亿美元),比2015年增长3.7%。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 石家庄家居市场加速变局
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

美国人:对于你们来说,干脆装成是加拿大人好了。英国人很难判断你们之间的区别,这样你们就可以避免卷入到关于死刑的尴尬谈话中了。
The decaying feet, some dating back to 1967, were being 'cleaned up', plumped up and whitened at the 'foul-smelling' plant using bleach and other chemicals, before being prepared for sale.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

二月的一天,苹果(Apple)的年度股东大会进行了一个多小时,蒂姆?库克(Tim Cook)已经耐心地回答了苹果进军电视市场的计划和他如何看待谷歌眼镜(Google Glass)等各类问题。但当一位参会听众就苹果各环保项目(比如其太阳能数据中心)的盈利能力向这位首席执行官发难的时候,库克发怒了。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

但是政客们究竟会做什么呢?虽然特朗普总统致力于让传统制造业岗位回流美国,但美国好几个州正在试验其他政策来帮助无保障的低收入工人。这些政策各有不同,既有大幅提高最低工资标准的措施,也有阻止雇主在最后一刻调整员工时间表的新规。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

富达国际(Fidelity International)旗下全球地产基金的投资组合经理德克?菲利帕(Dirk Philippa)也削减了在香港的投资,把配置比重从两年前相对基准超配6%至8%调整至超配1%。
Leading actress Sun Li played Zhou in the drama. Despite her age, Sun, who was born in 1982, still successfully presented a lovely and innocent teenage Zhou in the eyes of many audience members.
Adding a plant is beneficial, as nature is a subconscious link to energy. An orchid or bamboo plant is easy to maintain, while providing a refreshing element to your space.
6. 《火星救援》(The Martian)。在布满红色岩石的山坡与丘陵之间,雷利·斯科特(Ridley Scott)这部非常令人满意的太空西部片既源自一个历史悠久的类型,也源自他的殿堂级遗产。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

neg否认+lect选择→不选择→忽视,不顾
胰腺产生胰岛素,如果你的胰腺没有这样做,你需要人工注射胰岛素。因此,糖尿病患者必须进行的日常事例是检查他们的血糖,并且在必要时注射胰岛素。
中国的旅游业官员正力图在2014年扭转入境游客减少的情况,专家认为,如果能对其过时的旅行团进行改进并降低票价,这一计划就有可能实现。
How do you feel about workingwith Ei Aoki again in Aldnoah?

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

So, what does that mean for oil prices in 2015? It is anybody’s guess, but here are the top five variables that will determine the trajectory of oil prices over the next 12 months, in no particular order.
We learned about fetal surgery’s potential to change lives.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Some people remain attached to a theory that can be described as resource scarcity. At its heart this theory suggests that resource development follows a linear pattern in which low-cost resources are developed first, meaning that most if not all future development must be more costly. Unfortunately the history of the industry does not support this view. If anything the experience of the past few decades suggests that the opposite is true.
The prize sold for far more than the gallery's estimate of $50,000 to $100,000. The only other Nobel Peace Prize known to have sold at auction was a 1903 medal that brought nearly $17,000 in 1985.
在《星球大战:原力觉醒》后,迪士尼影业和卢卡斯影业承诺每年冬天推出一部星球大战系列电影,都将围绕原来的主题展开。
1.《雨人》
9.《老友记》中卡罗尔和苏珊的婚礼

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

新年英文祝福语大全Best wishes for the year to come! 恭贺新禧! Good luck in the year ahead! 祝吉星高照! May you come into a good fortune! 恭喜发财! Live long
We took further steps to implement the Internet Plus action plan and the national big data strategy.
根据弗雷斯特研究公司(Forrester Research)的预测,今年美国网络商店的销售额将达到2,940亿美元,约为全国零售总额的9%。据弗雷斯特预计,到2018年,电子商务将占到全美零售总额的11%,约4,140亿美元,其中通过平板电脑和智能手机进行的交易约占线上销售额的20%。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

但最近,回购势头开始减弱。跟踪回购比例最大的100家公司的标准普尔500回购指数最近创下了自2012年年中以来的首次下跌。随着股价连创新高,股票回购所产生的推动作用消失,公司投资较长期项目或使用多余现金进行收购变得更有价值。
v. 排

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 毕业租房 这些窍门要知道
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

It's the summer of 1983, and precocious 17-year-old Elio Perlman is spending the days with his family at their 17th-century villa in Lombardy, Italy. He soon meets Oliver, a handsome doctoral student who's working as an intern for Elio's father. Amid the sun-drenched splendor of their surroundings, Elio and Oliver discover the heady beauty of awakening desire over the course of a summer that will alter their lives forever.
As the title suggests, the show also features the mothers of the pupils and the way that they often pit their children against each other.
销量高峰每日售票量约1500万张,每秒售出近700张车票。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

['k?mpr?maiz]
Meme-sharing Facebook groups have become a new college tradition, Mic reported last week, with students across the country trading inside jokes and fighting battles with rival universities via screenshot and caption.
n. 慈爱,喜爱,感情,影响

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

She then turns back and pecks the man on the cheek, as the crowd erupts in cheers around them.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Do you often feel gloomy and down in the dumps?

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 北京存量房屋买卖合同公开征意见
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

If you like your comedy with a side of heart-warming feels and poignant cultural commentary, please look no further than The Big Sick, about a comedian who falls in love with a heckler. Their backgrounds could not be more different, which is relatable to anyone in a mixed race relationship.
The continued, albeit slower growth in prices tracks with recent data showing real estate investment ticked upward in October and sales had registered barely any negative impact from the new restrictions.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

adj. 泰然自若的,镇定的;摆好姿势不动的,静止的;平
考察指标包括“智力资本和创新”、“技术成熟度”、“区域重要城市”、“健康、安全与治安”、“交通和城市规划”、“可持续发展与自然环境”、“文化与居民生活”、“经济影响力”、“成本”和“宜商环境”。
n. 饰带,花边,缎带
立场:呼吁结束政府停摆局面

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

“One person quit on Facebook.”
“我跟她很像,我们真的就像一对老夫妇。”

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

单词intelligence 联想记忆:
[k?ud]

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Amazon founder Jeff Bezos rose to No. 3 on the list for the first time, thanks to the jump in in Amazon shares, which boosted his net worth to $72.8 billion.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

新晋的富翁包括第一位以戏剧制作人身份进入榜单的卡梅隆·麦金托什,WeWork的亚当·诺依曼和米格尔·麦凯尔维,以及图片分享网站Pinterest的创始人本·希伯尔曼和埃文·夏普。
Mr Baweja’s extensive analysis on the changing nature of globalisation suggests the prime factor behind the weakness of global trade growth (which for a long time expanded at twice the rate of global GDP) has been a slowdown in investment.
Plum Alley:
不过,这种风潮好像不是在表达如今的女人想穿什么,而是在逃避,认为最安全的着装方式是回归过去,我认为这种想法是错误的。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 让“绿色”成为地板产业的推进剂
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

我喜欢这个列表(很棒的观点),但是我觉得我要更详细的完善一下怎样成为一个高效老板或者经理。
Three Billboards Outside Ebbing, Missouri

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

France, one of the most visited countries in the world, ranks No. 9 overall. It is No. 2 in Cultural Influence and No. 6 in Power.
《老友记》里几乎都是白人演员,所以它在当时并不是一部以兼容并包著称的电视剧。剧中的主要角色没有一个是"非主流"。甚至乔伊还经常拿罗斯的第一个老婆是同性恋这事开玩笑,而且经常能在台词中看到性别歧视的只言片语。
It seems safe to predict lots more noise and very little progress for the rest of 2017. And that will continue to be a damaging combination for business and the UK economy.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

然而,制度也同样重要,因为它们设定了游戏规则。
The frame is easily assembled and attaches to paddle boards, kayaks, and rafts.
他通过电梯门递出一张纸条,上面写着"有人被困在电梯内,请叫物业来帮忙。"寄希望于有人可以捡到并来救他。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

中国官方国内生产总值(GDP)增速会超过6.5%吗?
现代中国经销商Wang Rongzhen7月20日向路透社指出,现代汽车已经缩减提供给中国进口经销商的产品阵容,仅提供一款车型供销售,而在中国国产的车型不断增加。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

It predicts index funds, or those that track commodities indices, to be back in the agricultural market in the second half of 2017, as they look for a hedge against inflation.
华盛顿暂时的“停战”能否持续?
很难想象《迷失》中若是没有杰克·谢帕德作主角,这部剧会变成什么样。大概只有编剧真的这样写了,我们才会知道答案吧。美国广播公司引进这部剧后,杰克·谢帕德这一角色本该在坠机事件中遇难,接着将由凯特在这部剧中担任更多的领导角色。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

The more powerful the passions and the more uncontained the ambitions, the more likely the democratic system will collapse into despotism.
Also called self-driving cars, autonomous cars have been making the news recently. Chief among them are Google's self-driving cars. Google's driverless cars have traveled over 480,000 kilometers (300,000 mi) with only two accidents, both of which were caused by humans. But self-driving cars aren't new. In fact, their concepts have arguably been around since the days of Leonardo da Vinci, who invented a spring-powered cart with a programmable steering device.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Effective bosses must be effective decision makers. He or she cannot vacillate over every tiny decision. Being able to make decisions quickly and decisively — and then take responsibility for the outcome (see number 2) — is an important business skill, especially when managing others。
James Bond Themes 10. "Diamonds Are Forever" by Shirley Bassey
DeMarcus Cousins, Serge Ibaka and Lou Williams were all dealt in advance of Thursday's 3 p.m. ET deadline, leaving role players like Taj Gibson and P.J. Tucker as the biggest names to move right before the buzzer.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

"We have a system here in America where if something is for you and if they find it, it gets to you, that's beautiful," he told US TV station WTAE.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
From the themed collection: 批发市场成不合格家居建材重灾区
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

年龄:43岁
But what will politicians actually do While President Trump is focused on bringing back traditional manufacturing jobs to America, different US states are experimenting with other policies to help low-paid precarious workers. These range from sharply higher minimum wages to new rules to stop employers changing staff schedules at the last minute.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

201512/415505.shtml
现在甚至还出现了标准的煽动剧本。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

赢家:猛龙
获奖者:哈里王子殿下

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 资本退潮 长租公寓重新洗牌
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

在这个风云变幻的世界,詹姆斯·邦德俘获了不少铁杆粉丝,是至今为数不多的仍在续拍的电影之一。在人们的意识里,无论发生什么事情,新的007电影依然会拍下去。
"For IBM, although they regularly top the list of U.S. patentees by volume of patents each year, the Top 100 Global Innovators listing evaluates not just volume, but also success, globalization and impact," said Bob Stembridge, analyst with Thomson Reuters.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

These are just some of the issues that will face New Yorkers next year. And then there’s the new drum set the neighbor’s son received for Christmas ...

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 解析LED行业“钱景”大趋势
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Pork and vegetable prices both dropped by more than 8 percent year-on-year.
达奇斯说:阿迪达斯在今年的12个月里增加了3400万名新粉丝。公司把粉丝们带动了起来,粉丝们一整年都在进行积极的讨论,公司因而从中受益。
他说,杂志和作者在这起最近发生的丑闻中都有不可推卸的责任,声明中还说,《肿瘤生物学》在2015年就已经因同行评议过程存在类似问题而撤销一些论文。
'Gangnam Style' beat 'Call Me Maybe' as the most trending pop song and 'Skyfall' topped 'Prometheus' as the most enquired about film.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

vt. 建议,推荐,劝告

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

But once again, Bryant said he's fine, that his health is fine, that his shot is fine, and he diverted the conversation elsewhere, largely to his teammates and the team's overall scheme.
在面试中,每个人都说自己又很强的团队合作能力,快速的学习能力。告诉我一些别的好嘛。
Statistics from another market research firm, Counterpoint, indicate that China shipped 465 million smartphones over the last year, accounting for nearly one-third of the global volume.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

If the oldest man ever elected president can “tweet like a kindergartner,” why not flip the script and see if a youngster can be elected to office and govern wisely?
competition

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

That an iPhone mini and a LTE license from the Chinese government this year or next could finally persuade China Mobile (CHL), with 700 million subscribers, to cut a deal with Apple.
An early iteration of Summly, called Trimit, was featured in Apple's app store in July 2011 on a list of new and noteworthy offerings. There it was noticed by the influential Silicon Valley blog TechCrunch and quickly came to the attention of an investment group led by Li Ka-shing. When D'Aloisio was approached over email by Li's people at Horizons Ventures, he was only 15-and so far mostly managed to conceal that fact. He'd never met with anyone in the tech world face to face, and the information he'd listed when he registered Trimit spoke only vaguely of a London technology company. It failed to mention that the company's management and technology teams-in fact, its entire workforce-consisted of a single kid in a suburban bedroom who wasn't yet old enough to drive.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

就业增长超出预期;

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

distract
Hua Xu Yin
Children and hobbies do not belong on a résumé. And never, ever say, "Now that my kids are in college, I'm ready to get back in the workforce."

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Here's how the pay of prime ministers and presidents of the world's biggest economies stacks up, according to official data and converted into US dollars at market rates.
He then proceeded to ram the violin through the canvas.
7成以上受访者表示,实现自我价值是创业的最大动机。
经济学人智库表示,尽管没有一个北美城市进入前20名,但是纽约的生活成本相对于其他美国城市有所上升。纽约与洛杉矶并列第27位成为美国最贵城市。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

通过比较不同地区指定类别的生活成本,《经济学人智库》指出,亚洲城市在食品上的购买成本最高,其中韩国首尔的食品价格最高。欧洲城市则是在休闲娱乐用品上的成本最高。
Men and women rated the strengths of their programme equally.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

n. 商业广告
chann管道+el表名词,“人或物”→航道
总部位于芝加哥的竞争对手科尔尼(AT Kearney)也在为领导层变动做准备,计划于2018年第一季度投票决定接替约翰奥利格(Johan Aurik)的人选。管理合伙人最多担任两个任期,而奥利格已经期满。预计他的继任者将专注于让科尔尼做大,摆脱中等规模参与者之列。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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15. An Amazing Coincidence One of the studios with the most on-screen diversity — it released “Trainwreck” and “Straight Outta Compton” (if also “Ted 2”) — and with the most female directors is Universal, which, as of early December, had gobbled up almost 24 percent of the year’s market share.
男性使用这个密码的几率是女性的2.8倍。

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